ORIGINAL ARTICLE
Year : 2021 | Volume
: 7 | Issue : 3 | Page : 332--338
Panax notoginseng saponins increases the blood concentration of nifedipine by inhibiting CYP3A4 enzyme through PXR- and CAR-Mediated pathway
Qiu-Hong Li1, Jiao Zhao1, Ai-Xia Ju1, Yong Hu1, Qing-Song Qie1, Hong-Bin Xiao1, Guang Xu2, Xi-Jun Wang1
1 Clinical Pharmacy Laboratory, Department of Pharmaceutics, School of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin, China
2 9601 Medical Center Drive, Rockville, MD, USA
Correspondence Address:
Prof. Xi-Jun Wang
National Chinmedomics Research Center, Metabolomics Laboratory, Department of Pharmaceutical Analysis, Heilongjiang University of Chinese Medicine, Heping Road 24, Harbin 150040
China
How to cite this article:
Li QH, Zhao J, Ju AX, Hu Y, Qie QS, Xiao HB, Xu G, Wang XJ. Panax notoginseng saponins increases the blood concentration of nifedipine by inhibiting CYP3A4 enzyme through PXR- and CAR-Mediated pathway.World J Tradit Chin Med 2021;7:332-338
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How to cite this URL:
Li QH, Zhao J, Ju AX, Hu Y, Qie QS, Xiao HB, Xu G, Wang XJ. Panax notoginseng saponins increases the blood concentration of nifedipine by inhibiting CYP3A4 enzyme through PXR- and CAR-Mediated pathway. World J Tradit Chin Med [serial online] 2021 [cited 2022 Aug 8 ];7:332-338
Available from: https://www.wjtcm.net/article.asp?issn=2311-8571;year=2021;volume=7;issue=3;spage=332;epage=338;aulast=Li;type=0 |
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