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Table of Contents
ORIGINAL ARTICLE
Year : 2021  |  Volume : 7  |  Issue : 3  |  Page : 332-338

Panax notoginseng saponins increases the blood concentration of nifedipine by inhibiting CYP3A4 enzyme through PXR- and CAR-Mediated pathway


1 Clinical Pharmacy Laboratory, Department of Pharmaceutics, School of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin, China
2 9601 Medical Center Drive, Rockville, MD, USA

Date of Submission12-Mar-2021
Date of Acceptance02-Apr-2021
Date of Web Publication9-Aug-2021

Correspondence Address:
Prof. Xi-Jun Wang
National Chinmedomics Research Center, Metabolomics Laboratory, Department of Pharmaceutical Analysis, Heilongjiang University of Chinese Medicine, Heping Road 24, Harbin 150040
China
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/wjtcm.wjtcm_52_21

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Keywords: CAR, CYP3A4, nifedipine, Panax notoginseng saponins, pharmacokinetics, PXR


How to cite this article:
Li QH, Zhao J, Ju AX, Hu Y, Qie QS, Xiao HB, Xu G, Wang XJ. Panax notoginseng saponins increases the blood concentration of nifedipine by inhibiting CYP3A4 enzyme through PXR- and CAR-Mediated pathway. World J Tradit Chin Med 2021;7:332-8

How to cite this URL:
Li QH, Zhao J, Ju AX, Hu Y, Qie QS, Xiao HB, Xu G, Wang XJ. Panax notoginseng saponins increases the blood concentration of nifedipine by inhibiting CYP3A4 enzyme through PXR- and CAR-Mediated pathway. World J Tradit Chin Med [serial online] 2021 [cited 2022 Jun 29];7:332-8. Available from: https://www.wjtcm.net/text.asp?2021/7/3/332/323491

This article is been retracted.






 

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Introduction
Materials and Me...
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