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| ORIGINAL ARTICLE |
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| Year : 2021 | Volume
: 7
| Issue : 3 | Page : 332-338 |
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Panax notoginseng saponins increases the blood concentration of nifedipine by inhibiting CYP3A4 enzyme through PXR- and CAR-Mediated pathway
Qiu-Hong Li1, Jiao Zhao1, Ai-Xia Ju1, Yong Hu1, Qing-Song Qie1, Hong-Bin Xiao1, Guang Xu2, Xi-Jun Wang1
1 Clinical Pharmacy Laboratory, Department of Pharmaceutics, School of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin, China
2 9601 Medical Center Drive, Rockville, MD, USA
| Date of Submission | 12-Mar-2021 |
| Date of Acceptance | 02-Apr-2021 |
| Date of Web Publication | 9-Aug-2021 |
Correspondence Address:
Prof. Xi-Jun Wang
National Chinmedomics Research Center, Metabolomics Laboratory, Department of Pharmaceutical Analysis, Heilongjiang University of Chinese Medicine, Heping Road 24, Harbin 150040
China
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/wjtcm.wjtcm_52_21
Keywords: CAR, CYP3A4, nifedipine, Panax notoginseng saponins, pharmacokinetics, PXR
How to cite this article:
Li QH, Zhao J, Ju AX, Hu Y, Qie QS, Xiao HB, Xu G, Wang XJ. Panax notoginseng saponins increases the blood concentration of nifedipine by inhibiting CYP3A4 enzyme through PXR- and CAR-Mediated pathway. World J Tradit Chin Med 2021;7:332-8 |
How to cite this URL:
Li QH, Zhao J, Ju AX, Hu Y, Qie QS, Xiao HB, Xu G, Wang XJ. Panax notoginseng saponins increases the blood concentration of nifedipine by inhibiting CYP3A4 enzyme through PXR- and CAR-Mediated pathway. World J Tradit Chin Med [serial online] 2021 [cited 2022 Jun 29];7:332-8. Available from: https://www.wjtcm.net/text.asp?2021/7/3/332/323491 |
This article is been retracted.
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